Which of these illustrates pleiotropy?

Options :

1. Matings between earless sheep and long eared sheep always result in short eared offspring

2. Wheat kerneis can range from white to red in color, a trait governed by multiple genes

3. Human cystic fibrosis causes many symptoms from respiratory distress to digestive problems

4. The genes for scarlet eyes and hairy body in fruit flies are located on the same chromosome