Question Details

Which of the following tests cannot be examined by Amniocentesis procedure?

Options

A

Chromosome analysis

B

Detecting genetic defects

C

Maturity of fetal lungs

D

None of these

Correct Answer :

None of these

Solution :

The correct option is None of these.

Amniocentesis is a prenatal procedure in which a small amount of amniotic fluid is extracted from the amnion sac surrounding the developing fetus. This fluid contains fetal cells and various chemicals that provide critical information about the health and development of the fetus.

Let us examine each of the options to understand why they can all be evaluated using amniocentesis:
1. Chromosome analysis: Fetal cells suspended in the amniotic fluid are isolated and cultured in a laboratory. By examining the chromosomes of these cells (karyotyping), doctors can identify chromosomal abnormalities such as Down syndrome (trisomy 21), Edwards syndrome (trisomy 18), and sex chromosome abnormalities.
2. Detecting genetic defects: DNA extracted from the cultured fetal cells can be analyzed to detect specific gene mutations. This allows for the diagnosis of inherited genetic disorders such as cystic fibrosis, Tay-Sachs disease, and sickle cell anemia.
3. Maturity of fetal lungs: In late pregnancy, amniocentesis can be performed to test the maturity of the fetus's lungs. This is done by measuring the levels of lung surfactants (such as the lecithin-to-sphingomyelin ratio) present in the amniotic fluid.

Since all of the listed tests can be performed using the amniocentesis procedure, none of them are incapable of being examined. Therefore, the correct option is "None of these".

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