When gene targetting involving gene amplification is attempted in an individual’s tissue to treat disease, it is known as :

The correct answer is Gene therapy.

Let us break down the concepts to understand why this is the correct choice:
1. Gene Therapy: This is a medical technique that involves introducing, removing, or altering genetic material (DNA or RNA) within an individual's cells and tissues to treat or prevent disease. When a disease is caused by a faulty or mutated gene, gene therapy can deliver a healthy copy of the gene, turn off the malfunctioning gene, or introduce a new gene to help fight the disease. Gene targeting and gene amplification (producing multiple copies of a target gene to increase its expression) are common strategies used within gene therapy to achieve therapeutic levels of the gene product.
2. Biopiracy: This refers to the commercial exploitation of naturally occurring biochemical or genetic material, often by obtaining patents that restrict its future use, without fair compensation to the community or country of origin. It is an ethical and legal issue rather than a medical treatment.
3. Molecular Diagnosis: This is a collection of techniques used to analyze biological markers in the genome and proteome (such as identifying specific mutations, viral DNA, or gene expression patterns) to diagnose a disease. It is diagnostic rather than therapeutic.
4. Safety Testing: This is a broad term for testing procedures designed to ensure that drugs, medical devices, or therapies are safe for human use, but it is not the name of the treatment itself.

Therefore, gene targeting and amplification applied to an individual's tissue for disease treatment is known as Gene therapy.