This type of thalassemia disease is Cooley anaemia
Correct Answer :
Beta-thalassemia
Solution :
The correct option is Beta-thalassemia.
Cooley's anemia is a severe form of thalassemia, which is an inherited blood disorder characterized by abnormal hemoglobin production. Specifically, Cooley's anemia is also known as Beta-thalassemia major.
Here is a step-by-step breakdown of why this classification is correct:
1. Hemoglobin Structure: Hemoglobin, the oxygen-carrying protein in red blood cells, is composed of two alpha chains and two beta globin chains. The synthesis of these chains is controlled by specific genes.
2. Beta-Thalassemia vs. Alpha-Thalassemia:
- Alpha-thalassemia occurs when there is a defect or mutation in the genes responsible for producing alpha globin chains.
- Beta-thalassemia occurs when there is a defect or mutation in the genes responsible for producing beta globin chains.
3. Cooley's Anemia: In 1925, the American pediatrician Thomas Benton Cooley first described this severe form of anemia. It represents the homozygous state of beta-thalassemia (Beta-thalassemia major), where both beta-globin genes are mutated, leading to a complete or near-complete lack of beta-globin chain synthesis. This results in severe anemia and requires regular blood transfusions.
Therefore, Cooley's anemia is classified under Beta-thalassemia.
Access expert-curated educational resources and study materials—completely free.
Create, conduct, and manage professional online assessments with Crey. Perfect for teachers and institutes.
Copyright © 2026 Crey. All Rights Reserved.