This regulates the enzymatic quantity in pancreatic juice
Correct Answer :
Pancreozymin
Solution :
The correct option is Pancreozymin.
To understand why this is the correct answer, let us break down the physiological regulation of pancreatic secretions step-by-step:
1. Composition of Pancreatic Juice: Pancreatic juice is composed of two main fractions: an aqueous bicarbonate component (rich in water and bicarbonate ions) and an enzymatic component (rich in digestive enzymes like amylase, lipase, and trypsinogen).
2. Hormonal Regulation: The secretion of these components is regulated by hormones released by the enteroendocrine cells of the duodenum in response to food entering from the stomach.
3. Secretin vs. Pancreozymin (CCK):
- Secretin primarily stimulates the duct cells of the pancreas to secrete a large volume of watery fluid rich in bicarbonate ions () to neutralize stomach acid.
- Pancreozymin (which is now known to be the same hormone as Cholecystokinin or CCK, often referred to as CCK-PZ) acts on the acinar cells of the pancreas to stimulate the secretion of a juice rich in digestive enzymes (the enzymatic quantity).
4. Conclusion: Historically and in specific contexts, Pancreozymin is the designated term that highlights the hormone's role in stimulating the release of pancreatic enzymes (hence "pancreo-" for pancreas and "-zymin" for enzyme). Therefore, it regulates the enzymatic quantity in pancreatic juice.
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