Question Details

This is the genotype of blood group A

Options

A

Iᴬ Iᴬ|

B

Iᴬ IO|

C

Iᴮ Iᴮ|

D

Iᴬ Iᴬ| or Iᴬ Iᴼ|

Correct Answer :

Iᴬ Iᴬ| or Iᴬ Iᴼ|

Solution :

The correct option is Iᴬ Iᴬ or Iᴬ Iᴼ.

In the ABO blood group system, the blood types are determined by three different alleles of a single gene: IA, IB, and IO (often written as i).

The alleles IA and IB are co-dominant with each other, meaning both will be expressed if present together (resulting in blood group AB). However, both IA and IB are completely dominant over the recessive IO allele.

For an individual to have blood group A, they must express the A antigen. Due to the dominance relationships, this phenotype can arise from two distinct genetic combinations:
1. Homozygous genotype (Iᴬ Iᴬ): The individual inherits the dominant IA allele from both parents.
2. Heterozygous genotype (Iᴬ Iᴼ): The individual inherits the dominant IA allele from one parent and the recessive IO allele from the other. Because IA is dominant, the recessive IO allele is masked, and the individual's blood type is A.

Therefore, the genotype for blood group A can be either Iᴬ Iᴬ or Iᴬ Iᴼ.

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