Question Details

This is an active cell death process

Options

A

apoptosis

B

necrosis

C

lysis

D

senescence

Correct Answer :

apoptosis

Solution :

The correct option is apoptosis.

Explanation:
Cell death can occur through different mechanisms, which are broadly classified based on whether they require energy and active cellular machinery (active processes) or are passive consequences of injury.

1. Apoptosis is a highly regulated, programmed cell death pathway. It is considered an active process because the cell actively participates in its own demise, requiring the activation of specific enzymes (such as caspases), gene expression, and the expenditure of energy in the form of ATP. During apoptosis, the cell shrinks, its chromatin condenses, and it breaks into membrane-bound apoptotic bodies that are cleanly engulfed by phagocytes without triggering an inflammatory response.

2. Necrosis, in contrast, is typically a passive, uncontrolled form of cell death resulting from severe external injury or trauma. It leads to cell swelling, membrane rupture, and the leakage of cellular contents, which induces inflammation in surrounding tissues.

3. Lysis refers to the physical bursting of a cell, which can be a mechanism or result of necrosis or osmotic pressure, rather than a programmed active pathway.

4. Senescence is a state of permanent cell cycle arrest where the cell remains metabolically active but stops dividing; it is not cell death itself.

Therefore, apoptosis is the designated active programmed cell death process.

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