This is a major risk linked with extreme ultraviolet rays through the atmosphere as a result of ozone layer depletion

The correct option is increased skin cancer.

Ozone layer depletion reduces the atmosphere's ability to filter out harmful ultraviolet (UV) radiation from the Sun, particularly UV-B and UV-C rays. When the ozone layer is thinned or depleted, a significantly higher amount of these high-energy ultraviolet rays reaches the Earth's surface.

Prolonged exposure to these ultraviolet rays damages the DNA in skin cells. This genetic damage can lead to mutations that cause skin cells to grow uncontrollably, resulting in a substantially increased risk of developing various types of skin cancers, including melanoma, basal cell carcinoma, and squamous cell carcinoma. Therefore, increased skin cancer is a major health risk directly linked to ozone layer depletion.