Question Details

This is a complication of haemophilia

Options

A

Bleeding in the head

B

joint swelling

C

death

D

All of the above

Correct Answer :

All of the above

Solution :

The correct option is All of the above.

Haemophilia is an inherited genetic bleeding disorder characterized by a deficiency in key clotting factors (Factor VIII in Haemophilia A, and Factor IX in Haemophilia B). Without sufficient levels of these factors, the body's coagulation cascade is impaired, making it difficult to form stable blood clots. This leads to several significant clinical complications:
1. Bleeding in the head (intracranial hemorrhage): This is one of the most serious and life-threatening complications of haemophilia. It can occur spontaneously or after minor trauma, causing pressure build-up in the skull, neurological damage, or stroke.
2. Joint swelling (haemarthrosis): Bleeding into joint spaces, particularly the knees, elbows, and ankles, is a hallmark complication of severe haemophilia. Repeated bleeding episodes cause chronic inflammation, swelling, pain, and can eventually lead to permanent joint damage and degenerative arthritis (haemophilic arthropathy).
3. Death: Severe, uncontrolled internal bleeding, especially in critical areas like the brain (intracranial hemorrhage) or gastrointestinal tract, can be fatal if not promptly treated with clotting factor replacement therapy.
Because all of these are recognized complications of haemophilia, "All of the above" is the correct choice.

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