Question Details

This disease falls under the same category as colourblindness in man

Options

A

Presbyopia

B

Haemophilia

C

Diabetes insipidus

D

Night blindness

Correct Answer :

Haemophilia

Solution :

The correct option is Haemophilia.

To understand why this is the correct choice, let us break down the genetic classification of these diseases:

1. Genetic Category of Colourblindness:
Colourblindness in humans is a classic example of an X-linked recessive disorder. This means the gene responsible for the condition is located on the X chromosome (one of the two sex chromosomes), and the trait is recessive. Therefore, males (who have only one X chromosome, XY) express the disease if they inherit a single mutated X chromosome, while females (who have two X chromosomes, XX) typically only express it if they inherit two copies of the mutated gene.

2. Comparing the Options:
Let us evaluate each of the given options to find which one shares this exact genetic category:

* Haemophilia: Like colourblindness, haemophilia is also an X-linked recessive disorder. It is caused by a deficiency in blood clotting factors (such as Factor VIII in Haemophilia A or Factor IX in Haemophilia B), leading to prolonged bleeding. Because the defective gene resides on the X chromosome, it follows the exact same pattern of inheritance as colourblindness.
* Presbyopia: This is an age-related vision condition caused by the gradual loss of flexibility in the eye's natural lens, making it difficult to focus on close objects. It is not an inherited X-linked genetic disorder.
* Diabetes insipidus: This condition is characterized by polydipsia (excessive thirst) and polyuria (excessive urination), caused by a deficiency of the hormone vasopressin (ADH) or a lack of response to it. While some rare forms can be genetic, it does not classically fall under the same primary inheritance category as colourblindness.
* Night blindness: This is most commonly caused by nutritional deficiency (specifically Vitamin A deficiency) or other ocular conditions, and is not categorized as an X-linked recessive genetic disorder like colourblindness.

Therefore, Haemophilia is the disease that falls under the same genetic category (X-linked recessive inheritance) as colourblindness in humans.

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