Question Details

The endoplasmic reticulum in rapidly dividing cells is

Options

A

absent

B

poorly developed

C

not functional

D

highly developed

Correct Answer :

poorly developed

Solution :

The correct option is "poorly developed".

To understand why the endoplasmic reticulum (ER) is poorly developed in rapidly dividing cells, we can break down the cell structure and functional requirements of such cells step-by-step:

1. Understanding the Role of the Endoplasmic Reticulum (ER):
The endoplasmic reticulum is a network of membranes inside a cell that is primarily responsible for the synthesis of proteins (specifically those destined for membranes, lysosomes, or secretion) and lipids. It also plays a key role in folding, modifying, and transporting these molecules to their proper destinations, often via the Golgi apparatus.

2. Metabolic Demands of Rapidly Dividing Cells:
Cells that are dividing rapidly, such as embryonic cells or cancer cells, have a primary focus on growth and replication. Their main metabolic activity is the quick synthesis of cytoplasmic proteins, nucleic acids, and organelles required to build two new daughter cells. They do not spend energy producing specialized secretory proteins or complex membrane proteins that require extensive processing by the ER.

3. Ribosomes and Protein Synthesis in Dividing Cells:
Since these cells need to produce proteins rapidly for their own cytoplasm, they contain a large number of free ribosomes floating in the cytosol. Free ribosomes synthesize cytoplasmic proteins directly into the cytosol, bypassing the endoplasmic reticulum. Consequently, there is a greatly reduced requirement for a complex network of rough endoplasmic reticulum (which is associated with protein secretion and membrane insertion).

4. Conclusion:
Because the metabolic machinery of rapidly dividing cells is streamlined for internal replication rather than synthesis and secretion of complex proteins, a highly developed ER network is not required. As a result, the endoplasmic reticulum in these cells is poorly developed.

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