Question Details

Parkinson’s disease is caused due to deficiency of

Options

A

GABA

B

Dopamine

C

Acetylcholine

D

Endorphins

Correct Answer :

Dopamine

Solution :

The correct answer is Dopamine.

Understanding Parkinson's Disease:
Parkinson's disease is a progressive neurological disorder that primarily affects movement and motor control. The condition is directly linked to the loss of nerve cells (neurons) in a specific part of the brain known as the substantia nigra.

The Role of Dopamine:
The nerve cells in the substantia nigra are responsible for producing dopamine, which is a key neurotransmitter (chemical messenger). Dopamine acts as a messenger between the brain and the nervous system, helping to coordinate and control smooth, balanced, and purposeful muscle movements.

Why Deficiency Leads to Parkinson's Disease:
When these specialized neurons become damaged or die, the production of dopamine drops significantly. Without adequate dopamine levels, the brain's ability to transmit movement signals to the body is impaired. This deficiency leads to the characteristic motor symptoms of Parkinson's disease, such as:
- Tremors (involuntary shaking of hands, arms, or legs)
- Muscle stiffness or rigidity
- Bradykinesia (slowness of movement)
- Postural instability and balance issues

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