Question Details

If the nuclei from an 8-celled stage of an embryo are transplanted into enucleated eggs, which of the following events is likely to take place

Options

A

recipient egg dies

B

donor nuclei die in the new environment

C

cleavage occurs but is arrested after some time

D

formation of viable embryo in the recipient eggs

Correct Answer :

formation of viable embryo in the recipient eggs

Solution :

The correct option is "formation of viable embryo in the recipient eggs".

Step-by-Step Explanation:

1. Understanding Nuclear Totipotency:
During the early stages of embryonic development, specifically up to the 8-cell stage, the blastomeres (embryonic cells) remain undifferentiated. The nuclei of these cells retain their totipotent state. Totipotency is the ability of a single cell or nucleus to divide and produce all of the differentiated cells in an organism, including extraembryonic tissues.

2. The Process of Nuclear Transplantation:
When a nucleus from one of these 8-cell stage blastomeres is transplanted into an enucleated egg (an egg cell from which the original nucleus has been removed), the enucleated egg provides a suitable cytoplasmic environment. The cytoplasm of the host egg contains all the necessary factors to reprogram the transplanted donor nucleus.

3. Reprogramming and Development:
Because the donor nucleus from the 8-celled stage is still totipotent and undamaged, the cytoplasmic signals in the recipient egg successfully activate the genes required for embryonic development. The reconstructed egg behaves like a normal zygote.

4. Resulting Outcome:
Consequently, the transplanted egg initiates cleavage, undergoes normal embryonic development, and ultimately leads to the formation of a viable embryo in the recipient eggs.

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