Erythropoietin hormone which stimulates R.B.C. formation is produced by :
Correct Answer :
Juxtaglomerular cells of the kidney
Solution :
The correct answer is Juxtaglomerular cells of the kidney.
Detailed Explanation:
Erythropoietin (EPO) is a glycoprotein hormone that plays a crucial role in regulating red blood cell (erythrocyte) production (erythropoiesis) in the body. When oxygen levels in the blood decrease (hypoxia), specialized cells detect this change and stimulate the synthesis and release of erythropoietin.
In adults, about 85% to 90% of erythropoietin is synthesized and secreted by the juxtaglomerular cells (or interstitial cells peritubular capillary bed) of the kidneys. The remaining portion is produced by the liver. Once released into the bloodstream, erythropoietin travels to the bone marrow, where it binds to receptors on erythroid progenitor cells, stimulating them to proliferate and differentiate into mature red blood cells.
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