Question Details

Enterogastrone is

Options

A

hormone secreted by intestinal mucosa

B

hormone secreted by mucosa

C

secreted by endocrine glands related to digestion

D

hormone secreted by gastric mucosa

Correct Answer :

hormone secreted by intestinal mucosa

Solution :

The correct option is "hormone secreted by intestinal mucosa".

What is Enterogastrone?
Enterogastrone is a collective term for any hormone secreted by the mucosa of the duodenum (the upper part of the small intestine) in response to the presence of lipids (fats), acid, or hyperosmotic fluids in the chyme. The primary role of enterogastrone is to inhibit gastric motility and gastric acid secretion, thereby slowing down the emptying of the stomach to allow sufficient time for digestion and absorption of nutrients in the small intestine.

Detailed Explanation:
1. Secretory Site: Enterogastrones are synthesized and released by endocrine cells located in the mucosa of the duodenum and jejunum (both of which are parts of the intestinal mucosa). It is not secreted by the gastric mucosa (stomach lining).
2. Hormones Included: Major enterogastrones include secretin, cholecystokinin (CCK), and gastric inhibitory polypeptide (GIP).
3. Mechanism of Action: When fatty or acidic food enters the duodenum from the stomach, the intestinal mucosa detects it and secretes enterogastrone into the bloodstream. The hormone travels to the stomach, where it slows down gastric contractions and reduces the secretion of hydrochloric acid (HCl), ensuring optimal digestive conditions in the small intestine.

Therefore, enterogastrone is correctly identified as a hormone secreted by the intestinal mucosa.

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