Chronic anaemia and multiple sclerosis are
Correct Answer :
autoimmune diseases
Solution :
The correct option is autoimmune diseases.
To understand why chronic anaemia (specifically autoimmune types like pernicious anaemia) and multiple sclerosis are classified under this category, we can break down the concepts step-by-step:
1. Understanding Autoimmune Diseases:
An autoimmune disease is a condition in which the body's immune system, which normally defends the body against foreign invaders like bacteria and viruses, mistakenly identifies its own healthy cells, tissues, or organs as foreign. As a result, it produces autoantibodies or activates immune cells to attack and damage these healthy tissues.
2. Analyzing Chronic Anaemia (Autoimmune Pernicious Anaemia):
Pernicious anaemia is a chronic type of anaemia where the body's immune system destroys parietal cells in the stomach lining. These cells are responsible for producing intrinsic factor, a protein crucial for the absorption of vitamin B12 in the small intestine. Without sufficient vitamin B12, the body cannot produce enough healthy red blood cells, leading to a chronic anaemic state. Since this is caused by self-directed immune destruction, it is an autoimmune disease.
3. Analyzing Multiple Sclerosis (MS):
Multiple Sclerosis is a chronic disease of the central nervous system. In MS, the body's immune system mistakenly attacks the myelin sheath, which is the protective covering around nerve fibers (axons) in the brain and spinal cord. This immune-mediated damage disrupts the transmission of electrical signals along the nerves, leading to various neurological symptoms. Hence, MS is also classified as an autoimmune disease.
4. Evaluating Other Options:
- Hereditary diseases are directly passed down from parents to offspring through genetic mutations (e.g., sickle cell anaemia or cystic fibrosis). While genetics can play a role in susceptibility, these diseases are not purely hereditary.
- Allergic diseases are hypersensitive responses of the immune system to harmless environmental substances called allergens (e.g., pollen or dust mites).
- Hormonal diseases result from the underproduction or overproduction of hormones by the endocrine glands (e.g., diabetes mellitus or hyperthyroidism).
Therefore, both chronic autoimmune anaemia and multiple sclerosis are characterized by the immune system targeting the body's own components, making them autoimmune diseases.
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