A painful disorder of the joints, Gouts is due to
Correct Answer :
deposition of uric acid at joints
Solution :
The correct option is deposition of uric acid at joints.
Step-by-step Explanation:
1. Understanding Uric Acid: Uric acid is a waste product formed during the normal breakdown of purines, which are natural substances found in our body's cells and in many foods. Under normal circumstances, uric acid dissolves in the blood, passes through the kidneys, and is eliminated from the body in urine.
2. Hyperuricemia: If the body produces too much uric acid or the kidneys excrete too little, uric acid builds up in the blood. This condition is known as hyperuricemia.
3. Crystal Formation: When uric acid levels in the blood remain high for a prolonged period, it can form needle-like crystals of monosodium urate in and around the joints.
4. Joint Inflammation and Pain: The deposition of these sharp, needle-like uric acid crystals in the joint spaces triggers an inflammatory immune response. This leads to the sudden, severe attacks of pain, swelling, redness, and tenderness characteristic of gout, most commonly affecting the joint at the base of the big toe.
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